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[00150] “Treatment-resistant schizophrenia” (TRS) is defined as an inadequate response to at least two antipsychotic drugs at the maximally tolerated dose within the recommended therapeutic range, in trials lasting six weeks or more.
This article opens with a brief history of pharmacologic treatment of schizophrenia. It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition of treatment-resistant schizophrenia.
It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment
Abstract. We report five cases of treatment-resistant schizophrenia that presented with prominent negative and positive symptoms. They fulfill the criteria of diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5).
If the address matches an existing account you will receive an email with instructions to reset your password Combined use of Amisulpride and Clozapine for Patients with Treatment-Resistant Schizophrenia. Brian Cook and Gerry Hoogenboom. Australasian Psychiatry 2016 12: 1, 74-76 Combined use of Amisulpride and Clozapine for Patients with Treatment-Resistant Schizophrenia Show all authors. Brian Cook 1.
Treatment-resistant schizophrenia (TRS) remains a great clinical challenge [1, 2]. Clozapine is the most efficacious antipsychotic drug for this population [2, 3], but many patients cannot tolerate clozapine due to its adverse drug reactions (ADRs) [3, 4].
Common food preservative may help to treat schizophrenia. New research suggests that a common food preservative could be the answer for treatment-resistant people with schizophrenia.
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