For the first time, a group of international scientists from China and the United States were able to breed the offspring of mice from an unfertilized egg. The results of the study are published in the Proceedings of the National Academy of Sciences.
Parthenogenesis – also called same-sex reproduction — is a form of reproduction of an organism without the use of male germ cells. This type of development is characteristic of some insects, fish, reptiles, scorpions, but not mammals, which include mice.
Earlier attempts to conceive and carry a fetus without the participation of males were unsuccessful due to genomic imprinting. Using another method, scientists managed to solve this problem. They extracted a mouse egg, used a CRISPR gene editing tool, and then implanted several cells back into the female’s uterus. As a result, several test subjects gave birth to 8 to 12 cubs, and all were born alive, but only one survived to puberty, although this is enough to continue offspring.
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